NEXOVAS M 50 Strip of tablet
Country of Origin: India
Medicine Type: Tablet
Composition: Cilnidipine 10 + Metoprolol 50 mg
Expiry Date: Nov -0001
Manufacturer: Macleods Pharmaceuticals Ltd.
View Details
Prescription: Required
Seller Information: TrustPill Venture
MRP* ₹173.25 23.00% Off
₹133.40
( Inclusive of all taxes )
Strip of tablet
₹133.40 per tablet
Description
About this medicine
This fixed dose combination of cilnidipine and metoprolol, is prescribed in hypertension with or without heart failure.
How to use
Cilnidipine is a promising 4th generation Ca2+ channel blocker with a rational pharmacological profile, i.e. dual L/N-type Ca2+ channel-blocking action. The blockade of N-type Ca2+ channels effectively suppresses neurohumoral regulation in the cardiovascular system, including sympathetic nervous system and renin–angiotensin–aldosterone system. Thus, cilnidipine is expected to be favorable for various types of complications of hypertension.
• Metoprolol blocks β1 adrenergic receptors of cardiomyocytes, thus it decreases the slope of phase 4 in the nodal action potential (reduces Na+ uptake) and prolongs repolarization of phase 3 (slows down K+ release). It also suppresses the norepinephrine-induced increase in the sarcoplasmic reticulum (SR) Ca2+ leak and the spontaneous SR Ca2+ release, which are the major triggers for atrial fibrillation.
Possible Side Effects
Report to the physician immediately if the patients are having any of these following symptoms:
• Dizziness
• Slow heart beat
• Headache
• Sleepy
• Blurred vision
• Problem in rising up after sitting and lying down
• Difficulty in climbing
Storage Information
Store at room temperature.
Safety Advice
Prescription Required
Use this medicine only after consulting a registered doctor.
Keep Away From Children
Store medicines safely and out of reach of children.
Storage Instruction
Store in a cool and dry place away from direct sunlight.
Do Not Self Medicate
Incorrect usage may cause side effects or allergic reactions.
Safety Advice
Prescription Required
Use this medicine only after consulting a registered doctor.
Keep Away From Children
Store medicines safely and out of reach of children.
Storage Instruction
Store in a cool and dry place away from direct sunlight.
Do Not Self Medicate
Incorrect usage may cause side effects or allergic reactions.

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